Phospholipid-based nanodrill technology for enhanced intracellular delivery of nano-sized cargos
Nanosized drug delivery systems typically enter the cell via endocytosis.However, a significant amount of the endocytosed cargo cannot effectively escape from the endosome, resulting in drug degradation.Therefore, there are several ongoing efforts to develop transmembrane delivery systems that could circumvent endocytosis.In this study, phospholipi